2',3'-Dideoxyguanosine

CAS: 85326-06-3

Ref. 3D-ND04069

Produktinformation

• Name: 2',3'-Dideoxyguanosine
• Synonyme: Dideoxy guanosine2',3'-Dideoxy-D-guanosine, 1-(beta-D-ribofuranosyl)-1H-1,2,4-triazole-3-carboxamide - 2-amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one (1:1), 2-amino-9-[(2R,5S)-5-(hydroxymethyl)tetrahydrofuran-2-yl]-3,9-dihydro-6H-purin-6-one, 2′,3′-Dideoxyguanosine, Dideoxyguanosine, Guanosine, 2',3'-dideoxy-, Guanosine, 2′,3′-dideoxy-

Beschreibung

2',3'-Dideoxyguanosine (ddG) is a nucleoside analog that is used in the treatment of HIV-1 and hepatitis B infections. It inhibits the enzyme aldehyde dehydrogenase, which prevents the production of energy from glucose, resulting in cell death. This drug has been shown to be effective against human lymphocytes infected with HIV-1. ddG has also been shown to inhibit splicing and human immunodeficiency virus (HIV) reverse transcriptase, as well as being active against murine leukemia cells. The effective dose for ddG is between 0.5 and 5 µM.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 251.25 g/mol
• Formel: C₁₀H₁₃N₅O₃
• Reinheit: Min. 95%
• Farbe/Form: Powder