2'-Deoxy-8-oxoguanosine

CAS: 88847-89-6

Ref. 3D-ND06344

Produktinformation

• Name: 2'-Deoxy-8-oxoguanosine
• Synonyme: 8-Hydroxy-2'-deoxyguanosine8-Oxo-2'-deoxyguanosine8-Oxo-dG2'-Deoxy-8-oxo-D-guanosine, 2'-Deoxy-8-Oxoguanosine, 2′-Deoxy-7,8-dihydro-8-oxoguanosine, 7,8-Dihydro-2'-deoxy-8-oxoguanosine, 7,8-Dihydro-8-oxo-2′-deoxyguanosine, 7,8-Dihydro-8-oxodeoxyguanosine, 8-Hydroxydeoxyguanosine, 8-Oxo-2'-deoxyguanine, 8-Oxo-2′-deoxyguanosine, 8-Oxo-7,8-dihydro-2'-deoxyguanosine, 8-Oxo-7,8-dihydrodeoxyguanosine, 8-Oxo-7-hydrodeoxyguanosine, 8-Oxo-dG, 8-Oxodeoxyguanosine, Ccris 8239, Guanosine, 2'-deoxy-7,8-dihydro-8-oxo-, Guanosine, 7,8-dihydro-2'-deoxy-8-oxo-, 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxy-2′-deoxyguanosine

Beschreibung

2'-Deoxy-8-oxoguanosine (8-OHdG) is a product of oxidative DNA damage. The presence of 8-OHdG in urine has been used to detect and measure the degree of oxidative DNA damage in humans and animals, which may be linked to cancer and aging. When 8-OHdG is excreted into urine, it can react with other molecules such as protein or inorganic phosphorus, causing more oxidative DNA damage. 2'-Deoxy-8-oxoguanosine has also been shown to cause cell toxicity by damaging the cell's squamous epithelium, leading to cancer.For the 15N5 labelled version please check ND09970.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 283.25 g/mol
• Formel: C₁₀H₁₃N₅O₅
• Reinheit: Min. 95 Area-%
• Farbe/Form: White Powder