2'-Deoxy-2'-fluoro-5-iodouridine

CAS: 55612-21-0

Ref. 3D-ND07901

Produktinformation

• Name: 2'-Deoxy-2'-fluoro-5-iodouridine
• Synonyme: 5-Iodo-2'-fluorouridine2'-Fluoro-5-iodo-2'-deoxyuridine, Uridine, 2'-Deoxy-2'-Fluoro-5-Iodo-, 5-Iodo-1-(2-Fluoro-2-Deoxyribofuranosyl)Uracil

Beschreibung

2'-Deoxy-2'-fluoro-5-iodouridine is a positron-emitting analog of the nucleoside, uridine. It is a model system for studying the sensitivity of cells to uptake and glycosidic bond formation in the presence of radioactive substrates. 2'-Deoxy-2'-fluoro-5-iodouridine has been shown to be taken up by tumor cells with high expression levels of IGF-I receptor, which may make it useful as a cancer diagnostic. This compound also inhibits herpes simplex virus type 1 (HSV1) replication in cell culture and induces HSV1 gene expression in cultured human foreskin fibroblasts. It has not been evaluated for use in humans.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 372.09 g/mol
• Formel: C₉H₁₀FIN₂O₅
• Reinheit: Min. 95%
• Farbe/Form: White Powder