5'-O-DMT-4-thiouridine

Ref. 3D-ND08429

Produktinformation

• Name: 5'-O-DMT-4-thiouridine
• Synonyme: 5'-O-DMT-4-thio-D-uridine
• Marke: Biosynth
• Beschreibung: 5'-O-DMT-4-thiouridine is a nucleoside analog that is used as a research tool in anticancer and antiviral studies. It is an activator of the phosphatase PP1 and has been shown to inhibit the growth of cultured human leukemia cells by inhibiting DNA synthesis. This compound has also been shown to be an inhibitor of HIV replication in vitro and in vivo, but it is not active against other viruses. 5'-O-DMT-4-thiouridine can be synthesized from uracil, 4-thiouracil, and DMT (dimethoxytrityl) using standard phosphoramidite chemistry. The purity of this compound is greater than 99%, and it can be obtained for use at a reasonable price.

Chemische Eigenschaften

• Molekulargewicht: 562.64 g/mol
• Formel: C₃₀H₃₀N₂O₇S
• Reinheit: Min. 95%