2'-Deoxy-5'-O-DMT-N6-methyladenosine

CAS: 98056-69-0

Ref. 3D-ND09159

Produktinformation

• Name: 2'-Deoxy-5'-O-DMT-N6-methyladenosine
• Synonyme: 2'-Deoxy-5'-O-DMT-N6-methyl-D-adenosine5'-O-DMT-N6-methyl-2'-deoxyadenosine, 5'-O-(Dimethoxytrityl)-N6-Methyl-2'-Deoxyadenosine, N6-Me-Dmt-Deoxyadenosine, 5'-O-DMT-N6-Methyl-2'-deoxyadenosine

Beschreibung

2'-Deoxy-5'-O-DMT-N6-methyladenosine is a mutant of the natural nucleoside adenosine which has been synthesized as a model for the study of the enzyme ribonucleotide reductase. The mutant has a frameshift mutation, and the resulting protein is unable to catalyze DNA synthesis. It can be complemented by adding wild type nucleotides to regenerate the original sequence. 2'-Deoxy-5'-O-DMT-N6-methyladenosine inhibits the synthetase activity of ribonucleotide reductase and also inhibits polymerization of erythromycin B and styrene.
2'-Deoxy-5'-O-DMT-N6-methyladenosine has been shown to inhibit dehydrogenase activity in auxotrophs of Escherichia coli.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 567.64 g/mol
• Formel: C₃₂H₃₃N₅O₅
• Reinheit: Min. 98 Area-%
• Farbe/Form: Off-White Powder