9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine

CAS: 20227-41-2

Ref. 3D-ND09204

Produktinformation

• Name: 9-(2'-Deoxy-2'-fluoro-β-D-arabinofuranosyl)adenine
• Synonyme: 2'-FANA-A6-Aminopurine-2'-fluoro-2'-deoxyarabinfuranoside
• Marke: Biosynth
• Beschreibung: 9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)adenine (9dFdA) is a potent inhibitor of the enzyme s-adenosylhomocysteine hydrolase, which is involved in the synthesis of adenosine. 9dFdA inhibits the growth of Trichomonas vaginalis and has shown good activity against other pathogens, such as Staphylococcus aureus and Mycobacterium tuberculosis. It also has been shown to have potent inhibitory activity against adenosine deaminase, which prevents an immune response by preventing cells from producing the amino acid adenosine. This compound also inhibits uridine phosphorylase, which is involved in nucleotide biosynthesis.

Chemische Eigenschaften

• Molekulargewicht: 269.24 g/mol
• Formel: C₁₀H₁₂FN₅O₃
• Reinheit: Min. 95%
• Farbe/Form: Powder