5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine

CAS: 119771-21-0

Ref. 3D-ND87794

Produktinformation

• Name: 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine
• Synonyme: 5'-Dfma, Adenosine, 5'-C-fluoro-5'-S-methyl-5'-thio-, (5'R)-, (5R)-5'-C-fluoro-5'-S-methyl-5'-thioadenosine

Beschreibung

5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine is an analogue of adenosine that has inhibitory activities on the biosynthetic pathway of polyamines. It has been shown to have a cytostatic effect on murine leukemia cells in vitro. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine inhibits the production of polyamines by interfering with the enzyme responsible for their biosynthesis, ornithine decarboxylase. 5'-Deoxy-5'-fluoro-5'-(methylthio)adenosine also inhibits the growth of murine leukemia cells and other leukemia cell lines, including L1210 and MM1.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 315.33 g/mol
• Formel: C₁₁H₁₄FN₅O₃S
• Reinheit: Min. 95%