Produktinformation
SR1664 is a non-peptide, synthetic, small molecule that binds to the fatty acid binding site on the PPARγ receptor. SR1664 has been shown to activate PPARγ and induce β-oxidation of fatty acids in vitro, leading to decreased triglycerides and cholesterol levels in mice. The pharmacokinetic properties of SR1664 are not yet well understood, but it may have potential for use as a pharmacological agent for treating metabolic disorders such as diabetes. The structural analysis of SR1664 reveals that it contains a hydroxyl group at position R3, which is responsible for its ability to bind to the receptor. SR1664 also has potent anti-inflammatory effects on liver cells due to its ability to block Toll-like receptor 4 (TLR4), which initiates inflammatory signaling pathways in response to lipopolysaccharide (LPS). This drug may have potential as an effective treatment for congestive heart failure or liver disease.
Chemische Eigenschaften
Technische Anfrage zu: 3D-NDC25905 SR1664
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