ent-idoxuridine

CAS: 162239-35-2

Ref. 3D-NE16541

Produktinformation

• Name: ent-idoxuridine
• Synonyme: 1-(2-Deoxy-b-L-erythro-pentofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione2'-Deoxy-L-5-iodouridine5-Iodo-2'-deoxy-L-uridine
• Marke: Biosynth
• Beschreibung: Ent-idoxuridine is a cytosolic DNA synthesis inhibitor that blocks the conversion of deoxycytidine to deoxyadenosine by inhibiting the enzyme deoxycytidine kinase. It is also an enantiomer of idoxuridine, which has the same mechanism of action. Ent-idoxuridine is not active against herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2). In contrast to idoxuridine, ent-idoxuridine is resistant to exonucleases and has been shown to be effective in treating immunodeficiency caused by HIV.

Chemische Eigenschaften

• Molekulargewicht: 354.1 g/mol
• Formel: C₉H₁₁IN₂O₅
• Reinheit: Min. 95%