2-Fluoroinosine
CAS: 83480-48-2
Ref. 3D-NF17964
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Produktinformation
- 9-b-D-Arabinofuranosyl-2-fluoro-1,9-dihydro-6H-purin-6-one9-b-D-Arabinofuranosyl-2-fluorohypoxanthine
2-Fluoroinosine is a chemical that inhibits protein synthesis by blocking the attachment of amino acids to their corresponding tRNA molecules. This drug is used in the treatment of cancer, as it inhibits cell growth and prevents tumor cells from dividing. 2-Fluoroinosine has been shown to be effective against human leukaemia cells, with its inhibitory properties being due to its ability to dephosphorylate the enzyme RNA polymerase II. This drug also has anti-malarial properties and can be used for the treatment of Chagas disease. 2-Fluoroinosine is synthesized from xanthosine, which is an intermediate in purine metabolism and can be obtained from naturally occurring sources or chemically through a solid phase synthesis.
2-Fluoroinosine is activated by UV light and can be synthesized using single stranded DNA or synthetases such as those found in calf thymus tissue. The catalytic mechanism of this drug has
Chemische Eigenschaften
Technische Anfrage zu: 3D-NF17964 2-Fluoroinosine
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