5-Fluorouridine-5'-triphosphate sodium salt

CAS: 3828-96-4

Ref. 3D-NF32079

Produktinformation

• Name: 5-Fluorouridine-5'-triphosphate sodium salt
• Marke: Biosynth
• Beschreibung: 5-Fluorouridine-5'-triphosphate sodium salt is an analog of uridine that has been used in the treatment of metastatic colorectal cancer. It is a prodrug that is metabolized to 5-fluorouracil, its active form. 5-Fluorouridine-5'-triphosphate sodium salt inhibits the synthesis of thymidylate, one of the precursors to DNA, and blocks the production of nucleotides. This results in cell lysis and death by apoptosis. The drug also inhibits epidermal growth factor receptor (EGFR), which may contribute to its antitumor effects.

Chemische Eigenschaften

• Molekulargewicht: 502.13 g/mol
• Formel: C₉H₁₄N₂O₁₅P₃F
• Reinheit: Min. 95%