5-Fluorocytosine arabinoside

CAS: 4298-10-6

Ref. 3D-NF78793

Produktinformation

• Name: 5-Fluorocytosine arabinoside
• Marke: Biosynth
• Beschreibung: 5-Fluorocytosine arabinoside (5FCA) is an analog of fluorocytosine and a degradable prodrug that is converted to fluorouracil (5FU) in the human liver. It acts as an inhibitor of DNA synthesis and has been used for the treatment of leukemias. 5-Fluorocytosine arabinoside is rapidly degraded by tissue culture cells, which may be due to its reactive functional groups. The inhibitory activity of this drug against cell culture was found to be minimal at low concentrations and reached a maximum at concentrations greater than 1 mM. The affinity ligands for this compound are reactive functional groups such as sulfhydryl, hydroxyl, and carboxyl groups, but not ester or amide bonds. This drug can be used in the synthesis of affinity ligands with a reactive functional group.

Chemische Eigenschaften

• Molekulargewicht: 261.21 g/mol
• Formel: C₉H₁₂FN₃O₅
• Reinheit: Min. 95%