[2'-18O]Guanosine

Ref. 3D-NG106386

Produktinformation

• Name: [2'-18O]Guanosine
• Synonyme: 9-(b-D-[2-18O]Ribofuranosyl)guanine
• Marke: Biosynth
• Beschreibung: [2'-18O]Guanosine is a novel antiviral that has shown antiviral activity against herpes simplex virus type 1 and cytomegalovirus. It also has anticancer effects, as it inhibits the growth of lymphoma cells by inhibiting DNA synthesis. [2'-18O]Guanosine is a modified nucleotide with an 18-oxygen atom in the 2' position, which prevents its use as a substrate for phosphodiesterases, thereby increasing its stability in vivo. [2'-18O]Guanosine is synthesized from the corresponding ribonucleotide, guanosine monophosphate (GMP), and can be used as an activator for DNA synthesis and an inhibitor of RNA synthesis.

Chemische Eigenschaften

• Molekulargewicht: 285.24 g/mol
• Formel: C₁₀H₁₃N₅₁₈OO₄
• Reinheit: Min. 95%