N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-adenosine

CAS: 163706-58-9

Ref. 3D-NGA70658

Produktinformation

• Name: N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-adenosine
• Synonyme: N6-(2-methylthioethyl)-2-(3,3,3-trifluoropropylthio)adenosine, N-[2-(Methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]adenosine

Beschreibung

The synthetic route to N-[2-(methylthio)ethyl]-2-[(3,3,3-trifluoropropyl)thio]-adenosine (MTEA), a nucleophilic nitro compound, begins with the chlorinating of methyl 2-hydroxyethyl thiocyanate with phosphorus oxychloride in an organic solvent. The chloroform is then removed by liquid chromatography and MTEA is obtained as a colorless liquid. It has been used for the industrial preparation of cangrelor, a pharmaceutical agent. Impurities such as 2-(methylsulfinyl)ethanol and 3,3,3-trifluoro-1-propanol are identified by using liquid chromatography.
The reaction time required for this process is 1 hour at 100°C.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 469.5 g/mol
• Formel: C₁₆H₂₂F₃N₅O₄S₂
• Reinheit: Min. 95%