5-Iodouridine

CAS: 1024-99-3

Ref. 3D-NI02225

Produktinformation

• Name: 5-Iodouridine
• Synonyme: 5-Iodouridine5-lodo-1-(b-D-ribofuranosyl)uracil5-Iodo-D-uridine, 5-Iodo-Uridine, 5-iodo-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione, Nsc 523375, Uridine, 5-iodo-, Uridine, 5-iodo- (8CI)(9CI)

Beschreibung

5-Iodouridine is a pyrimidine nucleoside that is found in the human body. It is used as a starting material for the synthesis of 5-iodo-2'-deoxyuridine, which has been shown to have biological properties. 5-Iodouridine binds to the dna template and prevents radiation from altering it's conformation. This binding has been shown to be specific for ultraviolet (UV) radiation, with little absorption at visible wavelengths. The biological effects of 5-iodouridine are dependent on its acidic pH and hydrogen bonding ability. In vitro assays have demonstrated that this compound can inhibit prostate cancer cells from proliferating and may be useful in treating cervical cancer.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 370.1 g/mol
• Formel: C₉H₁₁IN₂O₆
• Reinheit: Min. 95%
• Farbe/Form: White Powder