2',3'-O-Isopropylidene-6-thioinosine

CAS: 5856-48-4

Ref. 3D-NI08025

Produktinformation

• Name: 2',3'-O-Isopropylidene-6-thioinosine
• Synonyme: 2',3'-O-Isopropylidene-6-mercaptopurine riboside6-Mercapto-9-(2,3-O-isopropylidine-b-D-ribofuranosyl)purine
• Marke: Biosynth

Beschreibung

2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.
2',3'-O-Isopropylidene-6-thioinos

Chemische Eigenschaften

• Molekulargewicht: 324.36 g/mol
• Formel: C₁₃H₁₆N₄O₄S
• Reinheit: Min. 95%