2',3'-O-Isopropylidene-6-thioinosine

CAS: 5856-48-4

Ref. 3D-NI08025

Produktinformation

• Name: 2',3'-O-Isopropylidene-6-thioinosine
• Synonyme: 2',3'-O-Isopropylidene-6-mercaptopurine riboside6-Mercapto-9-(2,3-O-isopropylidine-b-D-ribofuranosyl)purine, 2′,3′-O-(1-Methylethylidene)-6-thioinosine, 2′,3′-O-Isopropylidene-6-mercaptopurine riboside, 2′,3′-O-Isopropylidene-6-thioinosine, 9-[2,3-O-(1-methylethylidene)pentofuranosyl]-3,9-dihydro-6H-purine-6-thione, 9H-Purine-6(1H)-thione, 9-(2,3-O-isopropylidene-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-, Furo[3,4-d]-1,3-dioxole, inosine deriv., Inosine, 2′,3′-O-(1-methylethylidene)-6-thio-, NSC 27305, 9H-Purine-6(1H)-thione, 9-(2,3-O-isopropylidene-β-D-ribofuranosyl)-

Beschreibung

2',3'-O-Isopropylidene-6-thioinosine is a fluorinated analogue of 6-thioguanine, which is an important precursor in the synthesis of nucleotides. The compound contains a fluorine atom at the 2' position and a sulfur atom at the 3' position of the ribose ring. It is soluble in organic solvents and can be used as a tracer for biochemical studies. The thermal stability of 2',3'-O-Isopropylidene-6-thioinosine has been demonstrated by molecular modelling and thermally induced filtration experiments. Molecular modeling has also shown that 2',3'-O-Isopropylidene-6-thioinosine binds to the active site of uridine phosphorylase, which is involved in pyrimidine salvage pathways in cells.
2',3'-O-Isopropylidene-6-thioinos

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 324.36 g/mol
• Formel: C₁₃H₁₆N₄O₄S
• Reinheit: Min. 95%