2'-O-Methyladenosine

CAS: 2140-79-6

Ref. 3D-NM05694

Produktinformation

• Name: 2'-O-Methyladenosine
• Synonyme: 2'-O-Methyl-D-adenosine
• Marke: Biosynth
• Beschreibung: 2'-O-Methyladenosine (2'-OMeA) is a nucleoside that is a low-energy analog of adenosine. It has been shown to be an effective inhibitor of protein synthesis in vitro, by inhibiting RNA polymerase in the process of transcription. 2'-OMeA has also been shown to inhibit virus replication in vitro and to have potent inhibitory activity against human immunodeficiency virus type 1 (HIV-1). 2'-OMeA inhibits viral replication by binding to the viral ribonucleotide reductase enzyme and blocking the conversion of ribonucleotides into deoxyribonucleotides. The chemical structures of 2'-OMeA are similar to those found in fatty acids and can be detected using chemical ionization mass spectroscopy. The sequence for 2'-OMeA was determined through sequencing methods including NMR spectroscopy and nuclear magnetic resonance data analysis.

Chemische Eigenschaften

• Molekulargewicht: 281.27 g/mol
• Formel: C₁₁H₁₅N₅O₄
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Off-White Powder