N-(4-(Diethylamino)phenethyl)-4-hydroxybenzamide

CAS: 2213490-89-0

Ref. 3D-NND49089

Produktinformation

• Name: N-(4-(Diethylamino)phenethyl)-4-hydroxybenzamide
• Marke: Biosynth
• Beschreibung: N-(4-(Diethylamino)phenethyl)-4-hydroxybenzamide (NDEA) is a drug that inhibits the enzyme 11β-hydroxysteroid dehydrogenase type 1, which converts cortisone to cortisol. It has been used in clinical trials for the treatment of acute and chronic inflammatory diseases, such as rheumatoid arthritis and ulcerative colitis. NDEA has been shown to inhibit the proliferation of neural progenitor cells in culture, thereby causing a decrease in neurogenesis. This effect may be due to its ability to inhibit glucocorticoid receptors on neural stem cells. This molecule also inhibits cell proliferation in cultured mouse hippocampal neurons.

Chemische Eigenschaften

• Molekulargewicht: 285.73 g/mol
• Formel: C₁₅H₁₂ClN₃O
• Reinheit: Min. 95%