2-Thiouridine

CAS: 20235-78-3

Ref. 3D-NT02881

Produktinformation

• Name: 2-Thiouridine
• Synonyme: 1-(beta-D-Ribofuranosyl)-2-thioxo-2,3-dihydro-4(1H)-pyrimidinone
• Marke: Biosynth
• Beschreibung: 2-Thiouridine is a uridine derivative that acts as a precursor for protein synthesis. It is synthesized from 2-amino-5-thiazole carboxylic acid and uracil in two steps, first with the formation of 2-thiouridine monophosphate and then with the conversion to 2-thiouridine diphosphate. The synthesis of 2-thiouridine is catalyzed by the enzyme uridine phosphorylase, which converts it to uridine monophosphate. 2-Thiouridine has been shown to have immunomodulatory effects in cell culture systems and animal models. These effects are believed to be due to its ability to act as an inhibitor of fatty acid synthase, which generates fatty acids from acetyl CoA. This process prevents the production of prostaglandins and leukotrienes, thereby reducing inflammation.

Chemische Eigenschaften

• Molekulargewicht: 260.27 g/mol
• Formel: C₉H₁₂N₂O₅S
• Reinheit: Min. 98 Area-%
• Farbe/Form: White Powder