Troxacitabine

CAS: 145918-75-8

Ref. 3D-NT29825

Produktinformation

• Name: Troxacitabine
• Synonyme: 4-Amino-1-((2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl)pyrimidin-2(1H)-one, (-)-Bch 204, (-)-OccC, 2(1H)-Pyrimidinone, 4-amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-, 2(1H)-Pyrimidinone, 4-amino-1-[2-(hydroxymethyl)-1,3-dioxolan-4-yl]-, (2S-cis)-, 4-Amino-1-[(2S,4S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]-2(1H)-pyrimidinone, 4-amino-1-[(2S)-2-(hydroxymethyl)-1,3-dioxolan-4-yl]pyrimidin-2(1H)-one, <span class="text-smallcaps">L</span>-OddC, Bch 4556, Spd 758, Troxacitabine,2(1H)-Pyrimidinone, 4-Amino-1-(2-(Hydroxymethyl)-1,3-Dioxolan-4-Yl)-, (2S-Cis)-, Troxatyl, α-<span class="text-smallcaps">L</span>-Dioxolane-C

Beschreibung

Troxacitabine is a nucleoside analog that inhibits DNA synthesis by selectively blocking the function of DNA polymerase. It has been shown to have potent antitumor activity in mouse tumor models and in a human breast cancer xenograft model. Troxacitabine has also been shown to inhibit the proliferation of renal cell cancer cells and induce apoptosis in these cells, as well as reduce the viability of cancer cells from other tumor types. Troxacitabine has also been shown to have an effect on body mass index and hematologic response, although it is not currently approved for use in humans.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 213.19 g/mol
• Formel: C₈H₁₁N₃O₄
• Reinheit: Min. 95%
• Farbe/Form: White To Off-White Solid
• InChl: InChI=1S/C8H11N3O4/c9-5-1-2-11(8(13)10-5)6-4-14-7(3-12)15-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7-/m0/s1
• InChI Key: InChIKey=RXRGZNYSEHTMHC-BQBZGAKWSA-N
• SMILES: Nc1ccn([C@@H]2CO[C@H](CO)O2)c(=O)n1