Produktinformation
- Gal-α1,4-Gal-β1,4-GlcNAc2-Acetamido-2-deoxy-4-O-([4-O-β-D-galactopyranosyl]-β-D-galactopyranosyl)-D-glucopyranose
The P1-antigen is a blood group antigen that is encoded by the gene. It is synthesized as a precursor protein of approximately 150 amino acids that undergoes proteolytic processing to generate two peptides, A and B, which are attached to the cell surface. The P1-antigen has been shown to be involved in transcriptional regulation and antimicrobial activity. It has also been shown to be present in metastatic colorectal cancer cells and its expression can be induced by trypsin treatment. The P1-antigen is also one of the most frequently studied proteins for its role in immune responses against bacteria, viruses, and parasites. This protein has been found to have response elements for several transcription factors including NF-κB, AP-1, NFAT, SP-1, and STAT3. The basic structure of this protein contains a diode region with two negatively charged regions that are critical for its function.
Chemische Eigenschaften
Technische Anfrage zu: 3D-OA09578 P1-Antigen
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