GM3NeuGc-Ganglioside

Ref. 3D-OG158639

Produktinformation

• Name: GM3NeuGc-Ganglioside
• Marke: Biosynth
• Beschreibung: Ganglioside GM3NeuGc (sodium salt) has a core disaccharide structure (Galβ1,4Glc) with N-glycolyl sialic acid linked α2,3 to the galactose residue, and ceramide linked β to position 1 on the reducing terminal glucose residue (Ledeen, 2009). GM3(NeuGc) ganglioside is of interest due to its restrictive expression in normal human tissues, according to immunohistochemical studies, using either polyclonal or monoclonal antibodies. However, both immunohistochemical and biochemical methods have strongly suggested its over-expression in human breast tumours (Oliva, 2006). It is seen as a possible tumor-associated carbohydrate antigen for cancer immunotherapy (Changping, 2019).

Chemische Eigenschaften

• Reinheit: Min. 95%
• Farbe/Form: White Powder