Gangliotriose

CAS: 1355005-58-1

Ref. 3D-OG29094

Produktinformation

• Name: Gangliotriose
• Synonyme: Asialo-GM2-trisaccharide
• Marke: Biosynth
• Beschreibung: Gangliotriose is the core trisaccharide structure in gangliosides, such as, GD2 (GalNAcβ1,4Galβ1,4Glc) (Ledeen, 2009). GD2 ganglioside is expressed at a low concentration in the central nervous system, nerves, skin melanocytes and stem cells in healthy adults. On the other hand, GD2 ganglioside is overexpressed in a number of tumors including: neuroblastoma, melanoma, small cell lung carcinoma and brain tumors. Recently, GD2 ganglioside has been found in low concentrations on breast cancer stem cells (CSC) that posess: self-renewal properties (division without disrupting the undifferentiated state), and tumor-initiating capabilities. It has been suggested that GD2 ganglioside may be developed as an effective target antigen for CSC immunotherapy (Fleurence, 2017).

Chemische Eigenschaften

• Molekulargewicht: 545.49 g/mol
• Formel: C₂₀H₃₅NO₁₆
• Reinheit: 90%Min
• Farbe/Form: Powder