Mycothiol - Stabilised with trifluoroacetic acid ammonium salt

CAS: 192126-76-4

Ref. 3D-OM58332

Produktinformation

• Name: Mycothiol - Stabilised with trifluoroacetic acid ammonium salt
• Synonyme: 1-O-[2-[[(2R)-2-(Acetylamino)-3-mercapto-1-oxopropyl]amino]-2-deoxy-?-D-glucopyranosyl]-D-myo-inositol disulfideAcCys-GlcN-Ins, 1-O-[2-[[(2R)-2-(Acetylamino)-3-mercapto-1-oxopropyl]amino]-2-deoxy-α-<span class="text-smallcaps">D</smallcap>-glucopyranosyl]-<smallcap>D</span>-myo-inositol, <span class="text-smallcaps">D</smallcap>-myo-Inositol, 1-O-[2-[[(2R)-2-(acetylamino)-3-mercapto-1-oxopropyl]amino]-2-deoxy-α-<smallcap>D</span>-glucopyranosyl]-, Mycothiol, U 17

Beschreibung

Mycothiol (MSH or AcCys-GlcN-Ins) is an unusual thiol compound found in the Actinobacteria. It is composed of a cysteine residue with an acetylated amino group linked to glucosamine, which is then linked to inositol. The oxidized, disulfide form of mycothiol (MSSM) is called mycothione, and is reduced to mycothiol by the flavoprotein mycothione reductase. Mycothiol biosynthesis and mycothiol-dependent enzymes such as mycothiol-dependent formaldehyde dehydrogenase and mycothione reductase have been proposed to be good drug targets for the development of treatments for tuberculosis.
This material is provided as a solid in dried buffer improve stability. MSH can readily be prepared from MSSM. Due to the rapid oxidation of MSH to MSSM, only MSSM can be shipped.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 970.97 g/mol
• Formel: C₃₄H₅₈N₄O₂₄S₂
• Reinheit: Min. 95%
• Farbe/Form: Colorless Powder