GM2-Oligosaccharide-sp-biotin

Ref. 3D-OO57595

Produktinformation

• Name: GM2-Oligosaccharide-sp-biotin
• Marke: Biosynth
• Beschreibung: Biotin-labelled oligosaccharide domain of the monosialylated glycosphingolipid GM2 of a-series. The compound is present on neuronal cells and plays a key role in the regulation of dendritogenesis in cortical pyramidal neurons. In lysosomal storage disorders Tay-Sachs and Sandhoff disease, where hexosaminases A and B are deficient, GM2 ganglioside accumulates in the nervous system. GM2 is also overexpressed in melanomas and other tumours of neuro-ecto origin. Moreover, the sugar moiety of this ganglioside is a receptor allowing viral infection of cells with reovirus and rotavirus.

Chemische Eigenschaften

• Molekulargewicht: 1,382.38 g/mol
• Formel: C₅₄H₈₈N₉O₂₉S•Na
• Reinheit: Min. 95%
• Farbe/Form: Powder