5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite

CAS: 194034-71-4

Ref. 3D-PA09015

Produktinformation

• Name: 5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite
• Synonyme: 5'-Amino-5'-deoxy-D-thymidine 3'-CE phosphoramidite
• Marke: Biosynth
• Beschreibung: 5'-Amino-5'-deoxy-5'-N-MMT-thymidine 3'-CE phosphoramidite is a high purity, novel, modified, antiviral and anticancer nucleotide. It is an analog of thymidine which has the methyl group at the 5' position replaced with a 5' amino group. This modification prevents conversion of the nucleoside to thymine and therefore inhibits DNA synthesis. The phosphoramidite is used as a building block for oligonucleotides in chemical synthesis. The phosphoramidite has shown antiviral activity against HIV by preventing reverse transcription of viral RNA into DNA. It also has been tested for its anticancer effects on human cells in vitro by inhibiting DNA synthesis and inducing apoptosis in cancer cells.

Chemische Eigenschaften

• Molekulargewicht: 713.8 g/mol
• Formel: C₃₉H₄₈N₅O₆P
• Reinheit: Min. 95%