Cyclo(Arg-Ala-Asp-D-Phe-Lys)

CAS: 756500-23-9

Ref. 3D-PCI-3883-PI

Produktinformation

• Name: Cyclo(Arg-Ala-Asp-D-Phe-Lys)
• Marke: Biosynth
• Beschreibung: Cyclo(Arg-Ala-Asp-D-Phe-Lys) is a cyclic peptide that has been shown to have antiangiogenic properties. It may be used as a linker for the conjugation of drugs to compounds with different target specificities. Cyclo(Arg-Ala-Asp-D-Phe-Lys) is a negative control peptide that has the RGD sequence, which is the most common motif in peptides that are used for cell targeting. This peptide was tested against human ovarian carcinoma and inhibited endothelial cell proliferation and tumor vasculature formation. Cyclo(Arg-Ala-Asp-D-Phe-Lys) also inhibited angiogenesis in vitro and in vivo, suggesting that it may be useful for the treatment of cancer and other diseases involving abnormal blood vessel growth.

Chemische Eigenschaften

• Molekulargewicht: 617.71 g/mol
• Formel: C₂₈H₄₃N₉O₇
• Reinheit: Min. 95%