2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite

Ref. 3D-PD09146

Produktinformation

• Name: 2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite
• Synonyme: 5'-(4,4'-Dimethoxytrityl)-N-(4-isopropylphenoxyacetyl)-2'-deoxyguanosine, 3'- [methyl-(N,N-diisopropyl)]-phosphoramiditeiPr-Pac-dG- Me Phosphoramidite2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)-D-guanosine 3'-Me phosphonamidite5'-O-DMT-N2-(4-is

Beschreibung

2'-Deoxy-5'-O-DMT-N2-(4-isopropylphenoxyacetyl)guanosine 3'-Me phosphoramidite is a modified nucleoside monophosphate with antiviral and anticancer activity. It is synthesized by the reaction of 2'-deoxyguanosine 5'-O-DMT (dG) with 4-isopropylphenoxyacetic acid in the presence of triethylamine and tetrazole. The product is purified by crystallization.
This compound has been shown to inhibit replication of human immunodeficiency virus type 1 (HIV-1) in human lymphocytes, which may be due to its ability to inhibit the synthesis of DNA, RNA, or both.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 907.03 g/mol
• Formel: C₄₉H₅₉N₆O₉P
• Reinheit: Min. 95%