2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite

CAS: 146954-75-8

Ref. 3D-PD09874

Produktinformation

• Name: 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite
• Synonyme: DMT-2′Fluoro-dU Phosphoramidite
• Marke: Biosynth
• Beschreibung: 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is a nucleotide that is used in the synthesis of DNA. It is an organic compound consisting of a molecule with a phosphate group at one end and a ribose sugar at the other. 2'-Deoxy-5'-O-DMT-2'-fluorouridine 3'-CE phosphoramidite is synthesized on a solid support by reacting nucleophilic reagents with the ribonucleoside. This drug has antineoplastic effects, inhibiting cancer cell growth by interfering with the production of ribonucleic acid (RNA) and protein synthesis. Hydrolysis of this drug releases fluorouracil, which inhibits thymidylate synthase, preventing the conversion of dUMP to dTMP, and thus blocking DNA synthesis.

Chemische Eigenschaften

• Molekulargewicht: 748.78 g/mol
• Formel: C₃₉H₄₆FN₄O₈P
• Reinheit: Min. 98 Area-%
• Farbe/Form: Powder