5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite

CAS: 251647-55-9

Ref. 3D-PD63448

Produktinformation

• Name: 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite
• Synonyme: DMT-2'-O-MOE-G(iBu)-CEP, 2'-O-Methyl-N2-Isobutyryl-5'-O-DMT-Guanosine-3'-CE-Phosphoramidite, Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite], Guanosine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite], 22: PN: US20030198965 PAGE: 20 claimed sequence, 18: PN: US20030211606 PAGE: 20 claimed sequence, 17: PN: US20030212017 PAGE: 20 claimed sequence

Beschreibung

Nucleoside phosphoramidites are used in the synthesis of oligonucleotides. Using a chemical approach allows quick and inexpensive access to custom-made oligonucleotides of the desired sequence. Enzymatic synthesis proceeds in a 5’ to 3’ direction, however the chemical synthesis is usually performed in the opposite direction. 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine 3'-CE phosphoramidite, also known as DMT-2'-O-MOE-G(iBu)-CEP, is a modified guanosine with a 2’-O-(2-methoxyethyl) group, these have been used in the synthesis of oligonucleotides as antisense drugs.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 913.99 g/mol
• Formel: C₄₇H₆₀N₇O₁₀P
• Reinheit: Min. 95%
• Farbe/Form: White Powder