5'-O-DMT-thymidine 3'-Me phosphoramidite

Ref. 3D-PD63539

Produktinformation

• Name: 5'-O-DMT-thymidine 3'-Me phosphoramidite
• Synonyme: dT-Me Phosphoramidite5'-(4,4'-Dimethoxytrityl)-thymidine, 3'-[methyl-(N,N-diisopropyl)]-phosphoramidite
• Marke: Biosynth
• Beschreibung: 5’-O-DMT-thymidine 3’-Me phosphoramidite is a novel and modified nucleotide analog that is used as an antiviral agent. It has been shown to be active against herpes simplex virus type 1 (HSV-1) and Epstein-Barr virus (EBV). 5'-O-DMT-thymidine 3’-Me phosphoramidite is not active against HIV, although it has been shown to inhibit the replication of Hepatitis B virus. This compound can also be used in cancer therapy.5'-O-DMT-thymidine 3' -Me phosphoramidite inhibits cellular DNA synthesis by competing with natural thymidine monophosphate (TMP) for incorporation into DNA. The incorporation of 5'-O-DMT-thymidine 3' -Me into DNA leads to a high frequency of mutations, which causes the death of the cell.

Chemische Eigenschaften

• Molekulargewicht: 705.78 g/mol
• Formel: C₃₈H₄₈N₃O₈P
• Reinheit: Min. 96 Area-%
• Farbe/Form: White Off-White Powder