Big Endothelin-2 (Human, 1-37)

CAS: 132699-72-0

Ref. 3D-PED-4222-S

Produktinformation

• Name: Big Endothelin-2 (Human, 1-37)
• Synonyme: Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-Gln-Thr-Ala-Pro-Tyr-Gly-Leu-Gly-Asn-Pro-Pro
• Marke: Biosynth
• Beschreibung: Amino acids 1-37 of the Human Big Endothelian-2 peptide formed as a result of furin cleavage of proendothelin which in turn is produced from EDN2 gene transcription. Due to the actions of the Endothelin-Converting Enzymes: ECE-1 and ECE-2, Big Endothelin-2 is converted into Endothelin-2 (ET-2) peptide. ET-2 has affinity for ETA and ETB G-protein coupled receptors which are found in a variety of tissues, including lungs, heart, kidneys, uterus and vasculature. It is believed that ET-2 is a potent vasoconstrictor and may play a role in cancer, immunology and heart failure. This product has is available as a 0.1mg vial and has disulfide bonds between Cys1-Cys15 and Cys3-Cys11.

Chemische Eigenschaften

• Molekulargewicht: 4,183.7 g/mol
• Formel: C₁₈₈H₂₆₉N₄₅O₅₆S₄
• Reinheit: Min. 95%