Big Endothelin-2 (Human, 1-38)

Ref. 3D-PED-4253-S

Produktinformation

• Name: Big Endothelin-2 (Human, 1-38)
• Synonyme: Cys-Ser-Cys-Ser-Ser-Trp-Leu-Asp-Lys-Glu-Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp-Val-Asn-Thr-Pro-Glu-Gln-Thr-Ala-Pro-Tyr-Gly-Leu- Gly-Asn-Pro-Pro-Arg

Beschreibung

Big Endothelin-2 is a 38 amino acid peptide formed as a result of furin cleavage of proendothelin which in turn is produced from EDN2 gene transcription. Due to the actions of the Endothelin-Converting Enzymes: ECE-1 and ECE-2, Big Endothelin-2 is converted into Endothelin-2 (ET-2) peptide. ET-2 has affinity for ETA and ETB G-protein coupled receptors which are found in a variety of tissues, including lungs, heart, kidneys, uterus and vasculature. It is believed that ET-2 is a potent vasoconstrictor and may play a role in cancer, immunology and heart failure. This product has is available as a 0.1mg vial.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 4,339.9 g/mol
• Formel: C₁₉₄H₂₈₁N₄₉O₅₇S₄
• Reinheit: Min. 95%