Hepcidin (canine)

Ref. 3D-PLP-3785-PI

Produktinformation

• Name: Hepcidin (canine)
• Synonyme: H-Asp-Thr-His-Phe-Pro-Ile-Cys-Ile-Phe-Cys-Cys-Gly-Cys-Cys-Lys-Thr-Pro-Lys-Cys-Gly-Leu-Cys-Cys-Lys-Thr-OH,Liver-Expressed Antimicrob ial Peptide (Dog), Hepcidin (dog)

Beschreibung

This product is a Liver-Expressed Antimicrobial Peptide of Canine source containing the disulfide Bonds: Cys7-Cys23, Cys10-Cys13, Cys11-Cys19, and Cys14-Cys22. Hepcidin is a peptide hormone that controls the release of iron from storage cells in the liver. It inhibits erythropoiesis by limiting the availability of iron for red blood cell production. This peptide also exhibits anti-microbial properties in that in response to inflammatory cytokines hepcidin leads to a decreased release of iron from enterocytes, hepatocytes and macrophages and further leads to ferroportin degradation and internalization. This product may be useful for use in research into disorders where iron dysregulation is paramount for pathogenesis and also in inflammatory diseases.

• Marke: Biosynth

Chemische Eigenschaften

• Reinheit: Min. 95%