Bid BH3 Peptide

Ref. 3D-PP47146

Produktinformation

• Name: Bid BH3 Peptide
• Synonyme: H-EDIIRNIARHLAQVGDSMDR-OH

Beschreibung

Peptide Bid BH3 Peptide is a Research Peptide with significant interest within the field academic and medical research. This peptide is available for purchase at Cymit Quimica in multiple sizes and with a specification of your choice. Recent citations using Bid BH3 Peptide include the following: Bid BH3 peptide, but not its mutant form G94E, induces permeability transition pore opening and cytochrome c release in vitro X Tian , J Chunsun , L Linjiang, Z Yong, J Haijing - Chinese Science , 2002 - Springerhttps://link.springer.com/article/10.1360/02tb9127 Relationship between helix stability and binding affinities: molecular dynamics simulations of Bfl-1/A1-binding pro-apoptotic BH3 peptide helices in explicit solvent V Modi , D Lama - Journal of Biomolecular , 2013 - Taylor & Francishttps://www.tandfonline.com/doi/abs/10.1080/07391102.2012.691363 BCL-2 selectively interacts with the BID-induced open conformer of BAK, inhibiting BAK auto-oligomerization SC Ruffolo, GC Shore - Journal of Biological Chemistry, 2003 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)86968-3/abstract All-atom model for stabilization of alpha-helical structure in peptides by hydrocarbon staples PS Kutchukian , JS Yang , GL Verdine - Journal of the , 2009 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja805037p The first alpha helix of Bax plays a necessary role in its ligand-induced activation by the BH3-only proteins Bid and PUMA PF Cartron , T Gallenne, G Bougras, F Gautier - Molecular cell, 2004 - cell.comhttps://www.cell.com/molecular-cell/pdf/S1097-2765(04)00653-7.pdf BIM and tBID are not mechanistically equivalent when assisting BAX to permeabilize bilayer membranes O Terrones, A Etxebarria, A Landajuela - Journal of biological , 2008 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)55169-7/abstract A stapled BID BH3 helix directly binds and activates BAX LD Walensky , K Pitter , J Morash, KJ Oh , S Barbuto - Molecular cell, 2006 - cell.comhttps://www.cell.com/fulltext/S1097-2765(06)00601-0 Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix LD Walensky , AL Kung , I Escher, TJ Malia, S Barbuto - science, 2004 - science.orghttps://www.science.org/doi/abs/10.1126/science.1099191 Conformational changes in Bax and Bcl-X^ sub L^ in response to Bid and Bim BH3 peptides L Billen, J Yethon, B Leber - Biochemistry and Cell , 2004 - search.proquest.comhttps://search.proquest.com/openview/99a26b007de32f844388d5e4285e5c3d/1?pq-origsite=gscholar&cbl=47596 A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro KJ Oh , S Barbuto, K Pitter , J Morash - Journal of biological , 2006 - ASBMBhttps://www.jbc.org/article/S0021-9258(20)72049-1/abstract Optimization and validation of mitochondria-based functional assay as a useful tool to identify BH3-like molecules selectively targeting anti-apoptotic Bcl-2 proteins J Long, L Liu, Z Nikolovska-Coleska, S Shangary - BMC , 2013 - Springerhttps://link.springer.com/article/10.1186/1472-6750-13-45 NMR determination that an extended BH3 motif of pro-apoptotic BID is specifically bound to BCL-XL H Ji, A Shekhtman , R Ghose - Magnetic , 2006 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/mrc.1856 Synthesis and Biophysical Characterization of Stabilized alpha-Helices of BCL-2 Domains GH Bird, F Bernal , K Pitter , LD Walensky - Methods in enzymology, 2008 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0076687908016224 Exploring the Activation Landscape of Pro-Apoptotic BAK Through the Discovery of Human BH3-Only and Non-Native Peptide Binders F Aguilar - 2022 - dspace.mit.eduhttps://dspace.mit.edu/handle/1721.1/144855 BH3 peptides induce mitochondrial fission and cell death independent of BAX/BAK EH Shroff, CM Snyder, GRS Budinger , M Jain - PLoS , 2009 - journals.plos.orghttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0005646 Rational Design of Regulators of Programmed Cell Death in Human Breast Cancer D Cowburn , ROCKEFELLER UNIV NEW YORK - 2000 - apps.dtic.milhttps://apps.dtic.mil/sti/citations/tr/ADA460041 Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax C Hockings , K Anwari, RL Ninnis, J Brouwer - Cell death & , 2015 - nature.comhttps://www.nature.com/articles/cddis2015105 A Novel Membrane-Permeable Breast-Targeting Pro-Apoptotic Peptide for Treatment of Breast Cancer B Guo, NORTH DAKOTA STATE UNIV FARGO - 2005 - apps.dtic.milhttps://apps.dtic.mil/sti/citations/tr/ADA474733 REPORT DOCUMENTATION PAGE OIMB No. 0704-0188 B Guo - 2005 - Citeseerhttps://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=9bb8c17e31993e0a9ecc5daef286c89b42e94acc

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 2,309.61 g/mol
• Formel: C₉₅H₁₆₁N₃₃O₃₂S