MAGE-A p248V9 scrambled

Ref. 3D-PP51095

Produktinformation

• Name: MAGE-A p248V9 scrambled
• Synonyme: H-RQYVELPYV-OH
• Marke: Biosynth
• Beschreibung: SB-peptide offers the scrambled version of MAGE-A p248V9. RQYVELPYV can be used as a negative control of MAGE-A p248V9 studies.SB-peptide offers also MAGE-A p248V9 (see section MAGE-A p248V9)).MAGE-A protein:MAGE-A p248V9, also kwon as multi-MAGE-A (YLEYRQVPV) is an epitope of Melanoma Antigen Gene expressed by tumors of different histological types and is a Cancer/Testis Antigens (CTA). Type of MAGE-A expressed in tumors cells varies according to the type of tumor. Targeting epitopes shared by all MAGE-A antigens would be interest in immunotherapy against a broad spectrum of cancers.Applications of MAGE-A p248V9 (multi-MAGE-A) :MAGE-A p248V9 is very useful because it could generate an HLA-A*02:01-restricted CTL response and shared by MAGE-A1,-A2,-A3,-A4,-A6,-A10 and -A12. MAGE-A p248V9 is used to stimulate specific cytotoxic T lymphocytes (CTL) in PBMCs and then to analyze CTL response especially the cytokine production by ELISPOT assay.Sequence : RQYVELPYV