Avosentan

CAS: 290815-26-8

Ref. 3D-QLA81526

Produktinformation

• Name: Avosentan
• Synonyme: Ro 67-0565, Spp 301
• CAS: 290815-26-8

Beschreibung

Avosentan is an endothelin receptor antagonist that has been shown to be a long-term effective treatment for chronic kidney disease in diabetic patients. It blocks the binding of endothelin-A to its receptor, which prevents the constriction and dilation of blood vessels. Avosentan has been shown to increase renal function by inhibiting tubulointerstitial injury and reducing the rate of progression of chronic kidney disease. This drug also has a positive effect on congestive heart failure, as it increases cardiac output and reduces afterload. Avosentan also stimulates growth factor production in heart tissue, which may account for some of its positive effects on cardiac function.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 479.51 g/mol
• Formel: C₂₃H₂₁N₅O₅S
• Reinheit: Min. 95%