MI 14

CAS: 1715934-43-2

Ref. 3D-QTC93443

Produktinformation

• Name: MI 14
• Marke: Biosynth
• Beschreibung: MI 14 is a nitroheterocycle compound that has been shown to have potent anticancer activity in animal models. The EC50 for MI 14 is 10 nM, and it has a more potent antitumor effect than the chemotherapeutic drug doxorubicin (EC50 = 20 nM). MI 14 also inhibits the production of pro-atherogenic lipids by activating PPARα, which may be useful in preventing cardiovascular disease. MI 14 is an inhibitor of PCSK9 with an IC50 value of 1 μM. It inhibits PCSK9-mediated LDL receptor degradation and thereby increases LDL receptor levels. This inhibition leads to increased clearance of LDL cholesterol from the blood and reduced plasma cholesterol levels. MI 14 also interacts with other drugs in its data base, such as warfarin, to increase their toxicity.

Chemische Eigenschaften

• Molekulargewicht: 450.9 g/mol
• Formel: C₁₉H₂₃ClN₆O₃S
• Reinheit: Min. 95%