(2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carboxylic acid 2,2,2-trifluoroacetic acid

CAS: 565453-41-0

Ref. 3D-QXA45341

Produktinformation

• Name: (2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carboxylic acid 2,2,2-trifluoroacetic acid

Beschreibung

(2S)-1-[2-[(3-Hydroxy-1-adamantyl)amino]acetyl]pyrrolidine-2-carboxylic acid 2,2,2-trifluoroacetic acid is an inhibitor that binds to the active site of protein kinase A (PKA). It is a noncompetitive inhibitor with a Ki of 0.03 μM for PKA. The inhibition of PKA by this drug has been shown to enhance the activation of glycogen synthase kinase 3β (GSK3β) and increase the phosphorylation of β-catenin at Ser33. This drug has also been shown to inhibit ion channels such as voltage gated sodium channels and calcium channels.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 436.4 g/mol
• Formel: C₁₉H₂₇F₃N₂O₆
• Reinheit: Min. 95%