4-(Phenylcarbamoyl)benzoic Acid

CAS: 16777-78-9

Ref. 3D-RAA77778

Produktinformation

• Name: 4-(Phenylcarbamoyl)benzoic Acid
• Synonyme: Terephthalanilicacid (8CI), Am 00

Beschreibung

4-(Phenylcarbamoyl)benzoic acid is a metabolite of all-trans-retinoic acid that has been shown to induce promyelocytic leukemia in human cells. It binds to cellular retinobenzoic acid receptors, which are proteins that regulate cellular differentiation and apoptosis. The binding of 4-(phenylcarbamoyl)benzoic acid to these receptors leads to the inhibition of cellular proliferation and the induction of apoptosis in promyelocytic leukemia cells. 4-(Phenylcarbamoyl)benzoic Acid also inhibits the metabolism of retinoids by inhibiting the enzyme retinol dehydrogenase, thereby increasing the levels of all-trans-retinoic acid. This leads to an increased activity of retinoic acid on its receptor.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 241.24 g/mol
• Formel: C₁₄H₁₁NO₃
• Reinheit: Min. 95%