4-Chloro-1H-benzimidazole

CAS: 16931-35-4

Ref. 3D-RAA93135

Produktinformation

• Name: 4-Chloro-1H-benzimidazole
• Marke: Biosynth
• Beschreibung: 4-Chloro-1H-benzimidazole is a synthetic nucleophile that reacts with thioethers to form an ion pair. It can be used as a precursor for the synthesis of captopril, an antihypertensive drug. 4-Chloro-1H-benzimidazole is also known to react with carboxylic acids to form ion pairs and then dehydrate to form electrostatically bound products. The reaction mechanism starts with the nucleophilic attack of a proton on the carbonyl carbon atom in the carboxylic acid, forming an intermediate carbocation which reacts with a chloride ion. This intermediate then collapses and forms two products: one positively charged and one negatively charged. The positively charged product is a chloroformate salt while the negatively charged product is an alcohol.

Chemische Eigenschaften

• Molekulargewicht: 152.58 g/mol
• Formel: C₇H₅ClN₂
• Reinheit: Min. 95%