2-Chloro-5,6-diphenylpyrazine

CAS: 41270-66-0

Ref. 3D-RBA27066

Produktinformation

• Name: 2-Chloro-5,6-diphenylpyrazine
• Synonyme: 5-Chloro-2,3-diphenylpyrazine

Beschreibung

2-Chloro-5,6-diphenylpyrazine is a potent, selective inhibitor of the prostacyclin receptor (IP). The IC50 is 0.3 μM and it has a Ki value of 4.1 μM. 2-Chloro-5,6-diphenylpyrazine has been shown to inhibit cancer cell proliferation in vitro and in vivo. It inhibits the growth of colon cancer cells HCT116 with an IC50 of 5 μM when used at a concentration of 10 μM or higher. 2-Chloro-5,6-diphenylpyrazine also inhibits the growth of prostate cancer cells PC3 with an IC50 of 7 μM when used at a concentration of 10 μM or higher.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 266.72 g/mol
• Formel: C₁₆H₁₁ClN₂
• Reinheit: Min. 95%