(1R,4R)-2,5-Diazabicyclo[2.2.1]heptane
CAS: 116183-84-7
Ref. 3D-REA18384
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Produktinformation
- 2,5-Diazabicyclo[2.2.1]heptane, (1R)-
- (1R)-2,5-Diazabicyclo[2.2.1]heptane
(1R,4R)-2,5-Diazabicyclo[2.2.1]heptane is an organic compound that is used as a substrate in the synthesis of esters and intermediates for functionalized advances. It can be obtained from epimerization of (1S,4S)-2,5-diazabicyclo[2.2.1]heptane by heating it with potassium hydroxide or sodium hydroxide in ethanol to form the methyl esters, which are then reacted with ammonia to form the lactam. (1R,4R)-2,5-Diazabicyclo[2.2.1]heptane can also be synthesized by reacting 1-chloro-3-methylpyrrolidinium iodide with 2-(aminomethyl)cyclohexanol and triethylamine in acetonitrile at room temperature with stirring to form