4-Bromo-1-methyl-1H-imidazole-5-carbaldehyde

CAS: 141524-74-5

Ref. 3D-RFA52474

Produktinformation

• Name: 4-Bromo-1-methyl-1H-imidazole-5-carbaldehyde
• Synonyme: 1H-Imidazole-5-carboxaldehyde, 4-bromo-1-methyl-, 4-Bromo-1-methylimidazole-5-carboxaldehyde, 4-bromo-1-methyl-1H-imidazole-5-carbaldehyde
• CAS: 141524-74-5

Beschreibung

4-Bromo-1-methyl-1H-imidazole-5-carbaldehyde (4BMICA) is a prodrug that has been shown to inhibit the growth of cancer cells by binding to the active site residues of the protein guanine nucleotide exchange factor (GEF) mcf-7. It is an analog of etoposide, which can act as a competitive inhibitor for the GEF. 4BMICA binds to and inhibits the activity of epidermal growth factor receptor (EGFR). This drug has been shown to have anti-inflammatory properties, as it inhibits lipid peroxidation and protein tyrosine nitration in rat liver microsomes.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 189.01 g/mol
• Formel: C₅H₅BrN₂O
• Reinheit: Min. 95%