Fosmanogepix

CAS: 2091769-17-2

Ref. 3D-RID76917

Produktinformation

• Name: Fosmanogepix

Beschreibung

Fosmanogepix is a new class of antifungal drug that belongs to the polyene family. It has shown clinical relevance in the treatment of candida glabrata and cryptococcus neoformans. Fosmanogepix inhibits the efflux pump activity in Candida glabrata and Cryptococcus neoformans, which are important for drug resistance. The MIC90 values of fosmanogepix against these two fungi were found to be 0.5 and 0.25 µg/mL, respectively. Fosmanogepix also inhibits protein synthesis and cell division by binding to intracellular targets such as DNA gyrase, topoisomerase IV, or ribonucleotide reductase enzymes. Clinical development is ongoing for this drug to treat fungal infections such as candida glabrata and cryptococcus neoformans.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 468.4 g/mol
• Formel: C₂₂H₂₁N₄O₆P
• Reinheit: Min. 95%
• Farbe/Form: Powder