Cauloside A

CAS: 17184-21-3

Ref. 3D-SAA18421

Produktinformation

• Name: Cauloside A
• Synonyme: (3beta)-3-(alpha-L-arabinopyranosyloxy)-23-hydroxyolean-12-en-28-oic acid, (3beta,5xi,18alpha)-3-(alpha-L-arabinopyranosyloxy)-23-hydroxyolean-12-en-28-oic acid, (3β,4α)-3-(α-<span class="text-smallcaps">L</span>-Arabinopyranosyloxy)-23-hydroxyolean-12-en-28-oic acid, 3-(alpha-L-Arabinopyransoyloxy)-23-hydroxy-olean-12-en-28-oic acid, 3-O-(alpha-L-Arabinopyranosyl)hederagenin, 3-O-Arabinopyranosylhederagenin, 3-O-[α-<span class="text-smallcaps">L</span>-Arabinopyranosyl]hederagenin, 3β-(α-<span class="text-smallcaps">L</span>-Arabinopyranosyloxy)-23-hydroxyolean-12-en-28-oic acid, Akebia saponin PA, Akeboside St_b, FJ-2 Acid, Fatsiaside B₁, Glycoside L-B₂, Hederagenin 3-O-α-<span class="text-smallcaps">L</span>-arabinopyranoside, Hederoside A₃, Kizuta saponin K₃, Koelreuteria saponin A, Leontoside A, Nepalin 1, Olean-12-en-28-oic acid, 3-(alpha-L-arabinopyranosyloxy)-23-hydroxy-, (3beta,4alpha)-, Olean-12-en-28-oic acid, 3-(α-<span class="text-smallcaps">L</span>-arabinopyranosyloxy)-23-hydroxy-, (3β,4α)-, Polypetaloside B, Prosapogenin CP₁, Saponin K₃, Scabioside A, Scabioside A (Patrinia), Tauroside B, β₂-Fatsin, δ-Hederin

Beschreibung

Cauloside A is a triterpenoid saponin that has been shown to have significant cytotoxicity against various cancer cells. Cauloside A has been shown to inhibit the proliferation of cancer cells and induce apoptosis through a mechanism that may involve inhibition of protein kinase C (PKC) activity and activation of caspases. Cauloside A also inhibits the growth of tumor xenografts in immunodeficient mice and reduces the incidence of metastasis. The pharmacokinetics of cauloside A has been studied in rats, with an elimination half-life of about 3 hours. This compound is absorbed from the gastrointestinal tract, but undergoes extensive first-pass metabolism in the liver.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 604.8 g/mol
• Formel: C₃₅H₅₆O₈
• Reinheit: Min. 95%