2-(4-Bromophenyl)propan-2-amine

CAS: 17797-12-5

Ref. 3D-SAA79712

Produktinformation

• Name: 2-(4-Bromophenyl)propan-2-amine
• Synonyme: 1-(1-Amino-1-methylethyl)-4-bromobenzene, 2-(4-Bromophenyl)Propan-2-Amine

Beschreibung

2-(4-Bromophenyl)propan-2-amine (BPAP) is an analogue of the antihistamine diphenhydramine. The BPAP analogues are selective for protein kinases, such as vegfr-2, cyclin, and cdk1. VEGFR-2 is a receptor tyrosine kinase that is activated by vascular endothelial growth factor and plays a role in angiogenesis. Cyclin is a serine/threonine protein kinase that regulates the cell cycle and CDK1 regulates the progression from G1 to S phase. In vivo efficacy studies have shown that BPAP inhibits these three kinases with an IC50 value of less than 1 μM in human tumor cells.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 214.1 g/mol
• Formel: C₉H₁₂BrN
• Reinheit: Min. 95%