(1R,2S)-Erythro-dihydro bupropion maleate

CAS: 292055-72-2

Ref. 3D-SLA05572

Produktinformation

• Name: (1R,2S)-Erythro-dihydro bupropion maleate
• Synonyme: (R*,S*)-2-(T-Butylamino)1-(3-Chlorophenyl) Propanol, (R*,S*)-2-(T-Butylamino)1-(3-Chlorophenyl) Propanol Maleate, (αR)-3-Chloro-α-[(1S)-1-[(1,1-dimethylethyl)amino]ethyl]benzenemethanol, erythro-Hydroxy Bupropion HCl, erythro-Hydroxybupropion, Benzenemethanol, 3-chloro-α-[(1S)-1-[(1,1-dimethylethyl)amino]ethyl]-, (αR)-

Beschreibung

(1R,2S)-Erythro-dihydro bupropion maleate (1) is a stereoselective drug that is metabolized by CYP2D6 to its active form, erythro-hydrobupropion. The prodrug has been shown to be an uptake inhibitor of acetaminophen in rat brain synaptosomes and increases the level of acetaminophen in plasma and brain tissue. (1R,2S)-Erythro-dihydro bupropion maleate has also been shown to be effective for depression in humans. It has been found that (1R,2S)-Erythro-dihydro bupropion maleate elutes at 6.8 minutes on an acetonitrile gradient and can be separated from its enantiomer by using a triple quadrupole mass spectrometer with a hplc-ms/ms method.

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 241.76 g/mol
• Formel: C₁₃H₂₀ClNO
• Reinheit: Min. 95%