4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline

CAS: 492444-39-0

Ref. 3D-SUA44439

Produktinformation

• Name: 4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline
• Synonyme: 4-Chloro-3-Cyano-6-Methoxy-7-[3-(4-Methylpiperazine-1-Yl)Propoxy]Quinoline

Beschreibung

4-Chloro-3-cyano-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]quinoline is an intermediate used in the preparation of bosutinib, a substance that is used in research. 4CMCMQ is obtained by reduction of the corresponding nitro compound with lithium aluminum hydride and then reacting it with 3-(4-methylpiperazin-1-yl)propanol. The reaction mixture contains impurities, which are identified as being an isomer of the desired product. The impurity can be removed by distillation or recrystallization. A number of controls are required to ensure the purity and safety of this drug, including tests for impurities and limits on residual solvents. Impurities found in 4CMCMQ include 2′,6′,2′′,6′′′-(2,3,6)-trimethylcycl

• Marke: Biosynth

Chemische Eigenschaften

• Molekulargewicht: 374.9 g/mol
• Formel: C₁₉H₂₃ClN₄O₂
• Reinheit: Min. 95%