2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid

CAS: 1343040-07-2

Ref. 3D-TDC04007

Produktinformation

• Name: 2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid
• Marke: Biosynth
• Beschreibung: The synthesis of 2-{Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid is accomplished through an asymmetric, stereoselective, catalytic route. The first step in the synthesis is conversion of glycine to the corresponding N-protected glycine methyl ester by reaction with benzyl chloroformate followed by protection of both carboxylic acid groups as FMOC derivatives. The key steps are a diastereoselective hydrogenation of the cyclopentane ring system and an efficient alkylation reaction of the resulting alcohol with 9H-fluoren-9-ol. 2-[Cyclopentyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino]acetic acid has been shown to be a potent inhibitor against bacterial growth. It binds to bacterial topoisomerase IV enzyme, which

Chemische Eigenschaften

• Molekulargewicht: 365.4 g/mol
• Formel: C₂₂H₂₃NO₄
• Reinheit: Min. 95%